Advice for pregnant women on the use of paracetamol

The Medicines and Healthcare products Regulatory Agency (MHRA) has published (23 September 2025) a clear statement on the safety of paracetamol use in pregnancy, stating that there is no confirmed link between taking paracetamol during pregnancy and autism in children.

Paracetamol is recommended as the first-choice pain reliever for pregnant women, used at the lowest dose and for the shortest duration.

Women with unresolved pain or fever, or those with concerns about the use of paracetamol, are urged to speak to a pharmacist, GP or midwifery team as soon as possible.

Professor Ranee Thakar, President of the Royal College of Obstetricians and Gynaecologists, said: “Managing pain and fever during and after pregnancy is really important for the wellbeing of women and their babies. Pain can impact a woman’s physical and psychological health, while unmanaged fevers can pose risks for both the mother and unborn baby.

The MHRA statement is clear that Paracetamol remains the recommended pain relief option for pregnant women when used as directed. It is vital that women have access to accurate, evidence-based information. If you are concerned or have questions about the use of paracetamol, please speak to your pharmacist or maternity team as soon as possible.”

For further information please visit:

Pregnancy, breastfeeding and fertility while taking paracetamol for adults – NHS